FAMU Interim Vice President of Research Kinfe Ken Redda has reached a
milestone in his research by receiving a patent for the development of
therapeutic agents in the treatment of HIV infection.
“A lot of
work, money and analysis were invested into this major discovery,” said
Redda. “We believe in our work. Our goal is certainly to make sure that
this discovery will lead to the development of a more effective drug
for the treatment of the HIV virus at an affordable price.”
Redda
and his research team were awarded United States Patent #8,314,143
titled “Synthetic Flavonoids and Pharmaceutical Compositions and
Therapeutic Methods of Treatment of HIV Infection and Other
Pathologies.”
“We have a long way to go before the right remedy
for treating HIV infection is realized,” said Redda. “I am excited that
we have taken the first step. This is a research activity that has
attracted me for the past quarter of a century. I know we need to do
more in trying to make drug molecules to be safer and effective. I’m
delighted to work with such a dedicated research group to reach this
stage.”
Redda, who is the principal investigator and co-inventor,
secured the patent with his research team. The patent relates to novel
therapeutic agents suitable for the treatment of humans afflicted HIV
infections.
This patent includes a group of compounds called flavonoids. Flavonoids
are present in vascular plants and are known for their wide range of
biological activities. According to Redda, the compounds his team has
developed are synthetic flavonoid derivatives designed to target a
specific enzyme, HIV integrase.
“HIV infection and AIDS are
serious health hazards affecting our society,” said Redda. “We are
proud to be part of the global efforts for a search of a more effective
treatment of the disease. Our compounds showed superior inhibitory
activities, compared to zidovudine (AZT), a popular drug used for HIV
treatment. There is great potential for this substance to become an
effective HIV and AIDS treatment.”
Redda’s research team consists
of Nelly Mateeva, an associate professor in FAMU’s Department of
Chemistry, and Chavonda Janeebra Mills, an associate professor at
Georgia College and State University. Mills was a doctorate student in
the FAMU College of Pharmacy and Pharmaceutical Sciences during the
initial process of their research.
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