Seth Ablordeppey, a FAMU professor in the
College of Pharmacy and Pharmaceutical Sciences, has received a United
States patent (No. 8,158,646) for extensive modifications to the drug
Cryptolepine. Preliminary tests indicate the drug will be effective at
treating infections commonly found in HIV/AIDS, chemotherapy, and organ
transplant patients. In addition, it has fewer side effects than several
currently used drugs.
“This research has been in the works for
more than a decade and I am grateful to FAMU for providing the
environment and opportunity for this discovery,” said Ablordeppey. “With
the discovery of these new agents we hope to deal one more blow to the
opportunistic infections that continue to wreak havoc in our
communities.”
Cryptolepine is a series of compounds derived from a
native plant of Ghana, West Africa. According to the Center for Disease
Control, opportunistic infections that attack weakened immune systems
have become increasing problematic in the United States. When compared
to drugs currently on the market, the high potency and fewer side
affects associated with Cryptolepine could ultimately combat this problem.
“I
am so very proud of Dr. Ablordeppey and the contribution he has made to
FAMU’s patent portfolio. Because of his work, FAMU now has a diverse
portfolio of pharmaceutical compounds that treat various diseases that
disproportionately affect African Americans,” said Tanaga Boozer,
director for FAMU Office of Technology Transfer, Licensing and
Commercialization. “His patent demonstrates the talent and commitment
among FAMU researchers to develop novel drugs, methods, and medical
devices that address health disparities in underrepresented
populations.”
This is the Ablordeppey’s second patent in two
years. In 2010, he received a patent for developing the “Haloperidol
Analog,” a method for treating mammals suffering from psychosis.